Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Aldh1a2  aldehyde dehydrogenase family 1, subfamily A2   (Synonyms: Aldh1a7, Raldh2, retinaldehyde dehydrogenase)
Results	Reference
1	J:220460 Andre P, Song H, Kim W, Kispert A, Yang Y, Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation. Development. 2015 Apr 15;142(8):1516-27
1	J:190545 Boulet AM, Capecchi MR, Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo. Dev Biol. 2012 Nov 15;371(2):235-45
1*	J:167039 Brade T, Kumar S, Cunningham TJ, Chatzi C, Zhao X, Cavallero S, Li P, Sucov HM, Ruiz-Lozano P, Duester G, Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2. Development. 2011 Jan;138(1):139-48
1*	J:156170 Castillo HA, Cravo RM, Azambuja AP, Simoes-Costa MS, Sura-Trueba S, Gonzalez J, Slonimsky E, Almeida K, Abreu JG, de Almeida MA, Sobreira TP, de Oliveira SH, de Oliveira PS, Signore IA, Colombo A, Concha ML, Spengler TS, Bronner-Fraser M, Nobrega M, Rosenthal N, Xavier-Neto J, Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer. Development. 2010 Feb;137(3):507-18
1*	J:171426 Chia I, Grote D, Marcotte M, Batourina E, Mendelsohn C, Bouchard M, Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice. Development. 2011 May;138(10):2089-97
1	J:138713 Cho A, Ko HW, Eggenschwiler JT, FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism. Dev Biol. 2008 Sep 1;321(1):27-39
1	J:67377 Chung AC, Katz D, Pereira FA, Jackson KJ, DeMayo FJ, Cooney AJ, O'Malley BW, Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan;21(2):663-77
1	J:178365 Cunningham TJ, Zhao X, Duester G, Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension. Genesis. 2011 Oct;49(10):776-83
1*	J:93148 Desai TJ, Malpel S, Flentke GR, Smith SM, Cardoso WV, Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut. Dev Biol. 2004 Sep 15;273(2):402-15
1	J:101263 Ivins S, Lammerts van Beuren K, Roberts C, James C, Lindsay E, Baldini A, Ataliotis P, Scambler PJ, Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1. Dev Biol. 2005 Sep 15;285(2):554-69
1	J:198634 Jurberg AD, Aires R, Varela-Lasheras I, Novoa A, Mallo M, Switching axial progenitors from producing trunk to tail tissues in vertebrate embryos. Dev Cell. 2013 Jun 10;25(5):451-62
1*	J:165715 Lee YJ, McPherron A, Choe S, Sakai Y, Chandraratna RA, Lee SJ, Oh SP, Growth differentiation factor 11 signaling controls retinoic acid activity for axial vertebral development. Dev Biol. 2010 Nov 1;347(1):195-203
1*	J:329046 Li B, Brusman L, Dahlka J, Niswander LA, TMEM132A ensures mouse caudal neural tube closure and regulates integrin-based mesodermal migration. Development. 2022 Sep 1;149(17):dev200442
1	J:301249 Lopez-Delgado AC, Delgado I, Cadenas V, Sanchez-Cabo F, Torres M, Axial skeleton anterior-posterior patterning is regulated through feedback regulation between Meis transcription factors and retinoic acid. Development. 2021 Jan 4;148(1):dev193813
1*	J:62941 Malpel S, Mendelsohn C, Cardoso WV, Regulation of retinoic acid signaling during lung morphogenesis. Development. 2000 Jul;127(14):3057-67
1	J:155154 Mesbah K, Harrelson Z, Theveniau-Ruissy M, Papaioannou VE, Kelly RG, Tbx3 is required for outflow tract development. Circ Res. 2008 Sep 26;103(7):743-50
1	J:91163 Mic FA, Sirbu IO, Duester G, Retinoic acid synthesis controlled by Raldh2 is required early for limb bud initiation and then later as a proximodistal signal during apical ectodermal ridge formation. J Biol Chem. 2004 Jun 18;279(25):26698-706
1*	J:97074 Molotkov A, Molotkova N, Duester G, Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development. Dev Dyn. 2005 Apr;232(4):950-7
1	J:108515 Molotkov A, Molotkova N, Duester G, Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. Development. 2006 May;133(10):1901-10
1*	J:39346 Niederreither K, McCaffery P, Drager UC, Chambon P, Dolle P, Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mech Dev. 1997 Feb;62(1):67-78
1*	J:308135 Okubo T, Hara K, Azuma S, Takada S, Effect of retinoic acid signaling on Ripply3 expression and pharyngeal arch morphogenesis in mouse embryos. Dev Dyn. 2021 Jul;250(7):1036-1050
1*	J:303813 Onimaru K, Tatsumi K, Tanegashima C, Kadota M, Nishimura O, Kuraku S, Developmental hourglass and heterochronic shifts in fin and limb development. Elife. 2021 Feb 9;10:e62865
1*	J:89166 Oosterveen T, Meijlink F, Deschamps J, Expression of retinaldehyde dehydrogenase II and sequential activation of 5' Hoxb genes in the mouse caudal hindbrain. Gene Expr Patterns. 2004 May;4(3):243-7
1	J:346126 Pappas MP, Kawakami H, Corcoran D, Chen KQ, Scott EP, Wong J, Gearhart MD, Nishinakamura R, Nakagawa Y, Kawakami Y, Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm. Development. 2024 Mar 1;151(5)
1	J:313346 Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, Ikegami K, Herriges MJ, Moskowitz IP, Zorn AM, Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development. Elife. 2021 Oct 13;10:e69288
1*	J:70836 Romand R, Albuisson E, Niederreither K, Fraulob V, Chambon P, Dolle P, Specific expression of the retinoic acid-synthesizing enzyme RALDH2 during mouse inner ear development. Mech Dev. 2001 Aug;106(1-2):185-9
1	J:170865 Ryckebusch L, Bertrand N, Mesbah K, Bajolle F, Niederreither K, Kelly RG, Zaffran S, Decreased levels of embryonic retinoic acid synthesis accelerate recovery from arterial growth delay in a mouse model of DiGeorge syndrome. Circ Res. 2010 Mar 5;106(4):686-94
1	J:136359 Sirbu IO, Zhao X, Duester G, Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway. Dev Dyn. 2008 Jun;237(6):1627-35
1	J:98489 Stennard FA, Costa MW, Lai D, Biben C, Furtado MB, Solloway MJ, McCulley DJ, Leimena C, Preis JI, Dunwoodie SL, Elliott DE, Prall OW, Black BL, Fatkin D, Harvey RP, Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62
1	J:81969 Vermot J, Niederreither K, Garnier JM, Chambon P, Dolle P, Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1763-8
1	J:213584 Vincent SD, Mayeuf-Louchart A, Watanabe Y, Brzezinski JA 4th, Miyagawa-Tomita S, Kelly RG, Buckingham M, Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo. Hum Mol Genet. 2014 Oct 1;23(19):5087-101
1	J:171613 Vitobello A, Ferretti E, Lampe X, Vilain N, Ducret S, Ori M, Spetz JF, Selleri L, Rijli FM, Hox and Pbx Factors Control Retinoic Acid Synthesis during Hindbrain Segmentation. Dev Cell. 2011 Apr 19;20(4):469-82
1*	J:62913 Wagner E, McCaffery P, Drager UC, Retinoic acid in the formation of the dorsoventral retina and its central projections. Dev Biol. 2000 Jun 15;222(2):460-70
1	J:272581 Wymeersch FJ, Skylaki S, Huang Y, Watson JA, Economou C, Marek-Johnston C, Tomlinson SR, Wilson V, Transcriptionally dynamic progenitor populations organised around a stable niche drive axial patterning. Development. 2019 Jan 2;146(1):dev168161
1*	J:156737 Zhao L, Saitsu H, Sun X, Shiota K, Ishibashi M, Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. Mech Dev. 2010 January - February;127(1-2):62-72